Adds a new compound attribute to an existing mysql CrudRepository which is part of the
#mysqlRepositoryCollection or an existing CrudRepository which is not part of
#mysqlRepositoryCollection.
This class uses a chromosome to approach a dbNSFP chromosome variant file, it then checks all locations recorded for
a chromosome in the data set, for every line, and uses a matching line to add annotation to the data set variant.
ExAC annotator
Data @ ftp://ftp.broadinstitute.org/pub/ExAC_release/release0.3/
TODO: feature enhancement: match multiple alternatives from SOURCE file to multiple alternatives in ExAC
e.g.
GoNl annotator data:
https://molgenis26.target.rug.nl/downloads/gonl_public/variants/release5_with_GTC/
release5_noContam_noChildren_with_AN_AC_GTC_stripped.tgz
PLUS chrX from http://molgenis15.target.rug.nl/release4_noContam_noChildren_with_AN_AC_GTC_stripped.tgz
GoNL example line: 1 126108 rs146756510 G A .
new ANN field replacing EFF:
ANN=A|missense_variant|MODERATE|NEXN|NEXN|transcript|NM_144573.3|Coding|8/13|c.733G>A|p.Gly245Arg|1030/3389|733/2028|
245/675||
-lof doesnt seem to work? would be great...
1000G annotator
Data @ http://ftp.1000genomes.ebi.ac.uk/vol1/ftp/release/20130502/
TODO: feature enhancement: match multiple alternatives from SOURCE file to multiple alternatives in 1000G
e.g.